Detailed Project Report (DPR) on Curcumin Extraction Plant (API and 95%) (Cap: 30 Kg/Day)

Detailed Project Report (DPR) on Curcumin Extraction Plant (API and 95%) (Cap: 30 Kg/Day)

CURCUMIN EXTRACTION PLANT (API AND 95%) (CAP: 30 KG/DAY)

[EIRI/EDPR/4728] J.C.: 2948XL

Curcumin (diferuloyl methane), the natural yellow pigment in turmeric, is isolated from the rhizomes of the plant Curcuma longa. It constitutes about 3-4% of the composition of turmeric. In the south and southeast tropical Asian countries, turmeric has been used for centuries as a spice to give the specific flavor and yellow color to curry. Turmeric became a very important spice to mankind when it was observed that the addition of turmeric powder in food preparation preserved its freshness and nutritive value.

Curcumin is also a powerful inhibitor of the proliferation of several tumor cells, as well as an anti-inflammatory agent. It exhibits anti-clastogenic, anti-fungal and anti-viral properties. However, the lack of information regarding the mechanisms of action of curcumin has precluded its clinical use in western countries. Several recent studies have given some insight into the molecular basis for the action of curcumin at the cellular level.


COST ESTIMATION

Plant Capacity            30 KG/Day

Land & Building (3000 sq.mt.)    Rs. 6.17 Cr

Plant & Machinery                    Rs. 1.41 Cr

Working Capital for 2 Months    Rs. 1.38 Cr

Total Capital Investment          Rs. 9.24 Cr

Rate of Return                          29%

Break Even Point                      51%


CONTENTS

INTRODUCTION

CHEMICAL STRUCTURE AND SELECTED PROPERTIES OF CURCUMIN (C21H20O6)

WHAT IS TURMERIC?

WHAT IS CURCUMIN?

PRODUCT SPECIFICATION

WHAT IS THE HISTORY OF TURMERIC AND CURCUMIN?

ARE THERE ANY SIDE EFFECTS OR INTERACTIONS?

WHY HASN’T THE PHARMACEUTICAL INDUSTRY PATENTED TURMERIC AND CURCUMIN?

DETAILS OF TURMERIC

INDIA TURMERIC GRADES

BENEFITS OF CURCUMIN AND ITS SIDE EFFECT

USES AND APPLICATION

IS MOSTLY USED IN THE FOLLOWING FIELDS:-

BIOLOGICAL SOURCE AND ACTIVITIES OF CURCUMIN

THE BIOLOGICAL SOURCE OF CURCUMIN

BIOLOGICAL ACTIVITIES OF CURCUMIN

ANTI-INFLAMMATORY PROPERTY

ANTIOXIDANT PROPERTIES

EFFECT OF CURCUMIN ON LYMPHOCYTES

EFFECT OF CURCUMIN ON PLATELET AGGREGATION

PROPERTIES OF CURCUMIN

CHEMICAL CHARACTERIZATION OF CURCUMIN

COMPOSITION OF THE FOOD ADDITIVE

PHYSICO-CHEMICAL PROPERTIES

CURCUMIN - THE YELLOW EXTRACT FROM TURMERIC

FIGURE:  CURCUMA LONGA (TURMERIC PLANT) WITH ITS RHIZOME OR ROOT

CHEMICAL COMPOSITION OF TURMERIC

BIOLOGICAL ACTIVITY OF TURMERIC AND ITS COMPOUNDS

PHARMACOLOGICAL ACTION OF TURMERIC AND ITS EXTRACT

FRAGRANCE AND FLAVOUR

RAW MATERIALS SCENARIO (INDIA AND GLOBAL)

INTERNATIONAL SCENARIO

MARKET OVERVIEW OF CURCUMIN

SOME OF THE MAJOR PARTICIPANTS IN THE GLOBAL CURCUMIN MARKET ARE

GLOBAL MARKET POSITION AND DEMAND OF CURCUMIN

U.S. CURCUMIN MARKET, BY APPLICATION, 2016-2024, (TONS)

ADDRESSES OF PRESENT MANUFACTURERS

MARKET ANALYSIS OF CURCUMIN

EXTRACTION OF CURCUMIN FROM TURMERIC

TABLE 1

METHODS, PRINCIPLES, AND CONDITIONS FOR EXTRACTION OF CURCUMINOIDS AND OLEORESIN

SEQUENCES IN CURCUMIN EXTRACTION

PROCESS FLOW DIAGRAM

STAGES IN CURCUMIN EXTRATION

PROCESS OUTLINE FOR CURCUMIN EXTRACTION

MANUFACTURING PROCESS OF CURCUMIN

RAW MATERIAL REQUIRED:

TECHNOLOGICAL PROCESS OF CURCUMIN EXTRACTION PLANT

PROCESS FLOW DIAGRAM

GRADE OF CURCUMIN

BASIC PLANT AND MACHINERY REQUIRED

SALIENT FEATURE OF THE PROCESS

MANUFACTURING PROCESS DIAGRAM

EXTRACTION AND PROCESSING OF CURCUMIN

TURMERIC HAS BEEN FOUND TO HAVE THE COMPOSITION AS SHOWN IN TABLE BELOW

TYPICAL COMPOSITION OF TURMERIC

FIGURE: THE THREE STRUCTURES OF CURCUMIN AND OTHER URCUMINOIDS

FIGURE TURMERIC RHIZOME AND CURCUMIN THAT WAS EXTRACTED

REFINEMENT OF CURCUMIN:

FILTRATION:

OLEORESIN TO CURCUMIN:

FIGURE – OLEORESIN TO CURCUMIN REFINEMENT PROCESS SET-UP

PURITY TESTING TECHNIQUES:

METHOD OF SUBCRITICAL CURCUMIN EXTRACTION

THE PRETREATED MATERIAL WILL BE LOADED INTO EXTRACTION POT.

ANALYSIS OF TURMERIC OIL

MATERIALS AND METHODS

PLANT RAW MATERIAL

FIGURE: FRESH TURMERIC RHIZOMES

DESCRIPTION OF EXPERIMENTAL SETUP AND METHOD

FIGURE: PROCESS FLOW DIAGRAM FOR PRODUCTION OF TURMERIC OIL

CALCULATION OF OIL YIELD AND MOISTURE CONTENT

MOISTURE CONTENT

TURMERIC OIL YIELD

TABLE: VARIATION OF % OIL YIELD WITH TIME

PHYTOCHEMICALS EVALUATION & CURCUMIN CONTENT OF TURMERIC

MATERIALS AND METHODS

CHEMICALS AND REAGENTS

COLLECTION AND PROCESSING OF PLANT MATERIAL

EXTRACTION PROCESS

PRELIMINARY PHYTOCHEMICAL EVALUATION OF CRUDE EXTRACT

GLYCOSIDES

ISOLATION OF CURCUMIN FROM TURMERIC RHIZOMES

EVALUATION OF ISOLATED CURCUMIN BY THIN LAYER CHROMATOGRAPHY (TLC)

FOURIER TRANSFORM INFRARED SPECTROSCOPY (FTIR) OF ISOLATED CURCUMIN

ESTIMATION OF CURCUMIN CONTENT IN TURMERIC RHIZOME

SWOT ANALYSIS OF CURCUMIN

STRENGTH

OPPORTUNITIES

WEAKNESSES

THREAT

LICENSES, CERTIFICATE AND QUALITY CONTROL FOR CURCUMIN EXTRACTION

FSSAI

AYUSH LICENSE (FOR MULTI PURPOSE EXTRACTION)

NOC

BUYERS LIST OF CURCUMIN AND TURMERIC OIL

SUPPLIERS OF RAW MATERIAL (INDIAN)

SUPPLIERS OF N-HAXANE

SUPPLIERS OF LABORATORY CHEMICALS

SUPPLIERS OF RAW MATERIAL (GLOBAL)

SUPPLIERS OF PLANT AND MACHINRY (IMPORTED)

CONSULTANT TURNKEY SUPPLIERS OF CURCUMIN EXTRACTION

ADDRESSES OF PLANT AND MACHINERY SUPPLIERS

SUPPLIERS OF CRUSHER

SUPPLIERS OF EVAPORATORS

SUPPLIERS OF FILTER PRESS

SUPPLIERS OF BOILERS

SUPPLIERS OF LAB TESTING EQUIPMENT

SUPPLIERS OF STORAGE TANK

SUPPLIERS OF MATERIAL HANDLING EQUIPMENTS

SUPPLIERS OF EXTRACTOR

SUPPLIERS OF STEAM DISTILATION PLANT

SUPPLIERS OF PUMPS

SUPPLIERS OF DIGITAL WEIGHING SCALE

SUPPLIERS OF OTHER MACHINERY


APPENDIX – A:

01. PLANT ECONOMICS

02. LAND & BUILDING

03. PLANT AND MACHINERY

04. OTHER FIXED ASSESTS

05. FIXED CAPITAL

06. RAW MATERIAL

07. SALARY AND WAGES

08. UTILITIES AND OVERHEADS

09. TOTAL WORKING CAPITAL

10. TOTAL CAPITAL INVESTMENT

11. COST OF PRODUCTION

12. TURN OVER/ANNUM

13. BREAK EVEN POINT

14. RESOURCES FOR FINANCE

15. INSTALMENT PAYABLE IN 5 YEARS

16. DEPRECIATION CHART FOR 5 YEARS

17. PROFIT ANALYSIS FOR 5 YEARS

18. PROJECTED BALANCE SHEET FOR (5 YEARS)

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