DEXTROSE I.V. SOLUTIONS 5%,
500 ML. CAPACITY, OUTPUT 50,000 BOTTLES/DAY
(FULLY AUTOMATED MACHINERIES)- MOLDING, WASHING, FILLING, SEALING, LABELLING AND SHRINKING
(CODE NO. 3172
Intra venous fluids, in general are used as I.V drips for patients in nursing homes and hospitals suffering from acute dehydration or considerable debilitating conditions. These I.V fluids replanish the body fluids. Though a number of I.V fluids are there, generally three types of I.V fluids are used in hospitals as I.V drips. They are as follows:-
1. Dextrose injection fluid
2. Dextrose and sodium chloride injection fluid
Types of IV Fluid
Crystalloid: Balanced salt/electrolyte solution; for msa true solution and is capable of passing through semi permeable membranes. May be isotonic, hypertonic or hypotonic. Normal Saline (0.9% NaCl), Lactated Ringer’s, Hypertonic saline (3, 5, & 7.5%), Ringer’s solution. However, hypertonic solutions are considered plasma expanders as they act to increase the circulatory volume via movement of intracellular and interstitial water into the intravascular space.
Colloid: High-molecular-weight solutions, draw fluid into intravascular compartment via on cotic pressure (pressure exerted by plasma proteins not capable of passing through membranes on capillary walls).Plasma expanders, as they are composed of macromolecules, and are retained in the intravascular space.
Free H2O solutions: provide water that is not bound by macromolecules or organelles, free to passthrough.D5W (5% dextrose in water), D10W, D20W, D50W, and Dextrose/crystalloid mixes. Blood products:
whole blood, packed RBCs, FFP, Cryoprecipitate, platelets, albumin. Essentially all colloids.
COST ESTIMATION
Plant Capacity : 50000.00 BOTTLES/day
Land & Building (4000 Sq.Mtrs) : us$. 2.26 Lacs
Plant & Machinery : US$. 16.90 Lacs
Working Capital for 2 Months : US$ 3.43 Lacs
Total Capital Investment : US$ 23.21 Lacs
Rate of Return : 40%
Break Even Point : 48%
• INTRODUCTION
• INTRAVENOUS FLUIDS
• IV FLUID/ELECTROLYTE THERAPY
• KEY TERMS
• DEXTROSE
• DEXTROSE SALINE INJECTION
• PROPERTIES
• REQUIREMENTS OF RAW MATERIALS
• EXPORT OPPORTUNITY OF INTRAVENOUS SOLUTION
• INTERNATIONAL MARKET OVERVIEW
• ECONOMIC PROFILE
• WORLD MARKET CONSUMPTION
• SOURCE OF MACHINES TECHNOLOGY
• OVERVIEW OF THE GLOBAL INTRAVENOUS SOLUTIONS MARKET
• IV FLUID PRODUCTION CAPACITY AND MARKET DEMAND IN AFGHANISTAN
• USES AND APPLICATION
• SOME GENERAL INTRAVENOUS FLUIDS
• MARKET SURVEY
• MARKET STRACTURE
• INDIAN BULK DRUG MARKET SHARE
• ADDITIONAL MARKET POSITION
• INDIAN PATENTS LAW, TRADE LAW & TAXATION
• 'TAX'ING INDIAN PHARMA
• PRESENT MANUFACTURES OF I.V FLUIDS
• SPECIFICATION OF INDIAN PHARMACOPEIA ON I.V FLUIDS
DEXTRAN INJECTION
• DEXTRAN 110 INJECTIONS
• B.I.S. SPECIFICATIONS FOR PLASTIC I.V. BOTTLES
• SODIUM CHLORIDE AND DEXTROSE INJECTION
• WATER THE EXCELLENT SOLVENT USED IN PHARMACY
• BASIC RAW MATERIALS
• REQUIREMENTS OF RAW MATERIALS AND SPECIFICATIONS
• COMPOSITION OF IV FLUID
• COMPOSITION OF COMMON IV FLUID (MEQ/L)
• COMPOSITION OF IV FLUIDS
• COMPOSITION OF COMMERCIAL I.V. FLUID AVAILABLE
• MANUFACTURING PROCESS OF I.V. FLUID (FFS TECHNOLOGY)
• PROCESS FLOW DIAGRAM
• PROCESS IN DETAILS
• FLOW DIAGRAM OF MANUFACTURING OF I.V. FLUIDS
• PLANT LAYOUT
• SWOT ANALYSIS
• SCHEMATIC DIAGRAM OF FFS PLANT LAYOUT
• FORM FILL SEAL TECHNOLOGY
• CALCULATING INTRAVENOUS FLOW RATES
• GENERAL PLANT LAYOUT
• MANPOWER
• LIST OF MACHINERY IV BAG PRODUCTION FORM FILL AND SEAL MACHINE
• CIP SYSTEM
• GUIDE TO GOOD MANUFACTURING PRACTICE (GMP) FOR MEDICINAL
• PRODUCT PRINCIPLE
• CLEAN ROOM AND CLEAN AIR DEVICE CLASSIFICATION
• CLEAN ROOM AND CLEAN AIR DEVICE MONITORING
• ISOLATOR TECHNOLOGY
• TERMINALLY STERILISED PRODUCTS
• ASEPTIC PREPARATION
• PERSONNEL
• PREMISES
• EQUIPMENT
• SANITATION
• PROCESSING
• STERILISATION
• STERILISATION BY HEAT
• MOIST HEAT
• STERILISATION BY RADIATION
• STERILISATION WITH ETHYLENE OXIDE
• FILTRATION OF MEDICINAL PRODUCTS WHICH CANNOT
• BE STERILISED IN THEIR FINAL CONTAINER
• FINISHING OF STERILE PRODUCTS
• SUPPLIERS OF RAW MATERIALS
• EMPTY IV BAG MANUFACTURER AND SUPPLIER IN INDIA
• COMPLETE PLANT SUPPLIERS
• SUPPLIERS OF PLANT AND MACHINEY
• CONSULTANT OF TURNKEY PROJECT SUPPLIER OF THE PLANT
AND MACHINERY
• CLEAN ROOM SUPPLIERS
APPENDIX – A:
1. COST OF PLANT ECONOMICS
2. LAND & BUILDING
3. PLANT AND MACHINERY
4. FIXED CAPITAL INVESTMENT
5. RAW MATERIAL
6. SALARY AND WAGES
7. UTILITIES AND OVERHEADS
8. TOTAL WORKING CAPITAL
9. COST OF PRODUCTION
10. PROFITABILITY ANALYSIS
11. BREAK EVEN POINT
12. RESOURCES OF FINANCE
13. INTEREST CHART
14. DEPRECIATION CHART
15. CASH FLOW STATEMENT
16. PROJECTED BALANCE SHEET
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