Industry Overview
Gelatin plays a vital role in the pharmaceutical industry, particularly in the manufacture of soft and hard capsules used for oral drug delivery. Capsules are often preferred over tablets because they are easier to swallow and can effectively deliver a wide range of pharmaceutical formulations. Soft gelatin capsules are typically manufactured using water or aqueous polyhydric alcohol-based formulations and commonly utilize low-bloom Type A gelatin (170–180 g), Type B gelatin (150–175 g), or a blend of both types. Hard gelatin capsules are produced in two separate parts that are later filled with the required medication. Their manufacture generally requires medium-to-high bloom gelatin, including Type A (250–280 g), Type B (225–250 g), or combinations of the two to achieve the desired strength and performance.
Beyond capsule production, gelatin serves multiple functions in pharmaceutical formulations. It is widely used as a binder or carrier in tablets, pastilles, and troches to improve product integrity and performance. Specialized pharmaceutical-grade gelatin is also employed in medical applications. A sterile absorbable gelatin sponge, commonly known as gel foam, is used during surgical procedures to help control hemorrhage. In addition, specially processed Type B gelatin can function as a plasma expander in specific medical applications. These diverse functional properties make gelatin an essential raw material across pharmaceutical manufacturing and healthcare products.
Cost Estimation
| Particular | Value |
|---|---|
| Plant Capacity | 3840000 Nos/Day |
| Land & Building (3250 sq.ft.) | Rs. 3.90 Cr |
| Plant & Machinery | Rs. 7.80 Cr |
| Working Capital for 0.5 Month | Rs. 31.34 Lacs |
| Total Capital Investment | Rs. 12.58 Cr |
| Rate of Return | 37% |
| Break Even Point | 54% |
Content Index
- INTRODUCTION
- GELATIN DETAILS AND PROPERTIES
- PROPERTIES OF EMPTY CAPSULE
- MARKET OVERVIEW
- BIS SPECIFICATIONS
- INDIAN STANDARD SPECIFICATION FOR GELATIN, FOOD GRADE
- INDIAN STANDARD SPECIFICATION FOR GELATIN, MICROBIOLOGICAL GRADE
- CHEMICAL COMPOSITION AND STRUCTURE OF GELATIN
- MANUFACTURERS/EXPORTERS/SUPPLIERS
- PROCESS OUTLINE
- MANUFACTURING PROCESS STEPS
- ENGINEERING DESIGN CONSIDERATIONS
- RAW MATERIAL AND SUPPLY
- ETP FACILITY
- SEWAGE AND WASTE WATER EFFLUENT
- PLANT & MACHINERY
- PLANT AND MACHINERY SUPPLIERS
- PRINCIPLES OF PLANT LAYOUT
- PLANT LOCATION FACTORS
- ANTICIPATED ENVIRONMENTAL IMPACTS
- MITIGATION MEASURES (PROPOSED)
- HEALTH SAFETY AND ENVIRONMENT
- SAFETY & OCCUPATIONAL MEASURE
- PROPOSED IMPLEMENTATION SCHEDULE
- PRELIMINARY LAYOUT
- PROJECT FINANCIALS
- CONCLUSIONS
Appendix
- 01. PLANT ECONOMICS
- 02. LAND & BUILDING
- 03. PLANT AND MACHINERY
- 04. OTHER FIXED ASSESTS
- 05. FIXED CAPITAL
- 06. RAW MATERIAL
- 07. SALARY AND WAGES
- 08. UTILITIES AND OVERHEADS
- 09. TOTAL WORKING CAPITAL
- 10. TOTAL CAPITAL INVESTMENT
- 11. COST OF PRODUCTION
- 12. TURN OVER/ANNUM
- 13. BREAK EVEN POINT
- 14. RESOURCES FOR FINANCE
- 15. INSTALMENT PAYABLE IN 5 YEARS
- 16. DEPRECIATION CHART FOR 5 YEARS
- 17. PROFIT ANALYSIS FOR 5 YEARS
- 18. PROJECTED BALANCE SHEET FOR (5 YEARS)
Frequently Asked Questions
Pharmaceutical gelatin is primarily used to manufacture capsules and as a functional ingredient in medicines. It is widely used in soft and hard capsules because of its excellent film-forming, binding, and dissolving properties. In addition to capsules, gelatin serves as a binder or carrier in tablets, pastilles, and troches. Certain specially processed gelatin grades are also used in medical products such as absorbable gelatin sponges for controlling surgical bleeding and plasma expanders.
Gelatin capsules are often preferred because they are easy to swallow and suitable for various formulations. They can accommodate powders, granules, liquids, and semi-solid fills depending on capsule type. Their smooth surface, rapid disintegration, and compatibility with many pharmaceutical ingredients make them a popular dosage form for manufacturers and patients alike.
Soft and hard gelatin capsules differ mainly in their construction and applications. Soft capsules are produced as sealed, one-piece dosage forms and commonly contain liquid or semi-solid formulations. Hard capsules are manufactured in two separate parts that are later filled with the required pharmaceutical material. Different bloom strength gelatin grades are selected to provide the mechanical properties required for each capsule type.
Key considerations include raw materials, manufacturing equipment, quality standards, plant layout, and environmental management. A successful project also requires suitable engineering design, reliable utility systems, wastewater treatment, compliance with applicable specifications, occupational safety measures, and an efficient implementation plan to support consistent pharmaceutical production.
Pharmaceutical gelatin should comply with applicable quality and regulatory specifications. The report references BIS specifications along with Indian standards for food-grade and microbiological-grade gelatin. Manufacturers typically verify physical, chemical, and microbiological characteristics to ensure the material is suitable for pharmaceutical applications and delivers consistent product performance.
Gelatin is also used in tablets, pastilles, troches, surgical products, and specialized medical formulations. It functions as a binder or carrier in solid dosage forms and is utilized in sterile absorbable gelatin sponges to assist with surgical hemostasis. Specially prepared gelatin grades may also be used in plasma-expanding formulations for specific medical applications.
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