Detailed Project Report (DPR) on orthopaedic implants and instruments plates, screws & nails (stainless steel, titanium & carbon fiber)

Detailed Project Report (DPR) on orthopaedic implants and instruments plates, screws & nails (stainless steel, titanium & carbon fiber)

ORTHOPAEDIC IMPLANTS AND INSTRUMENTS PLATES, SCREWS & NAILS (STAINLESS STEEL, TITANIUM & CARBON FIBER)
[CODE NO.3454]  



Orthopedic implants can be defined as medical devices used to replace or provide fixation of bone, or to replace articulating surfaces of a joint. In simpler words, orthopedic implants are used to either assist or replace damaged or troubled bones and joints. Orthopedic implants are mainly made from stainless steel and titanium alloys for strength and lined with plastic to act as artificial cartilage in order to reduce the stress at the articulating surfaces. Some implants are cemented into place and others are pressed to fit, so that your bone can grow into the implant for strength. Some examples of orthopaedic implants are: orthopaedic plates, orthopaedic nails, and orthopaedic screws. The key factor that guides bone healing is the interfragmentary movement, which determines the tissue strain and consequently the cellular reaction in the fracture healing zone. Thus, the methods of fracture fixation will be evaluated by considering their ability to reduce the interfragmentary movement. To achieve good and acceptable healing results, biomechanical principles should be understood and carefully taken into consideration.

Orthopedic implants are mainly made from stainless steel and titanium alloys for strength and lined with plastic to act as artificial cartilage. Few are cemented into place and others are pressed to fit so that your bone can grow into the implant for strength.


COST ESTIMATION

Plant  Capacity                                                 :       ORTHOPAEDIC IMPLANT AND INSTRUMENTS          
land & Building (5 Acres)                               :       Rs.    5.38 Cr
Plant & Machinery                                            :       Rs.    12.41 Cr
Working Capital for 2 Month                          :        Rs.    4.3   Cr
Total Capital Investment                                :         Rs.    23.00 Cr
Rate of Return                                                  :         41%
Break Even Point                                             :         44%


INTRODUCTION    
WHY DO NEED FOR ORTHOPEDIC IMPLANTS ARISE?    
ADVANTAGES & DISADVANTAGES OF ORTHOPEDIC IMPLANTS    
TYPES OF ORTHOPEDIC IMPLANTS    
TODAY’S IMPLANTS    
ANOTOMY OF BONE    
MATERIALS FOR ORTHOPAEDIC IMPLANT    
METALS    
POLYMERS    
CERAMICS    
IMPLANT PROPERTIES AND TISSUE RESPONSE    
USES & APPLICATIONS    
CARBON FIBER IMPLANTS    
CARBON FIBER REINFORCED PEEK BONE PLATE WITH TITANIUM
FIXATION SCREWS    
A BONE PLATE (100; 200) AND A SCREW (600), COMPRISING:    
CARBON FIBER REINFORCED COMPOSITE IMPLANT IN ORTHOPEDIC SURGERY
MEDICAL APPLICATION OF CARBON FIBER IMPLANTS    
WOUND HEALING PRODUCTS    
BIOCOMPATIBILITY    
OVERVIEW OF ORTHOPAEDIC INDUSTRY    
DRIVERS, RESTRAINTS, AND OPPORTUNITIES    
GLOBAL ORTHOPEDIC IMPLANTS MARKET KEY PRODUCT SEGMENT    
LAMEA INCLUDES MOROCCO ORTHOPEDIC IMPLANTS MARKET    
GLOBAL ORTHOPEDICS MARKET    
OVERVIEW OF INDIAN ORTHOPEDIC MARKET    
INDIAN ORTHOPEDICS MARKET – MARKET SIZE AND COMPETITIVE LANDSCAPE    
MARKET COMPOSITION, STRUCTURE AND SIZING    
GROWTH IN THE JOINTS SEGMENT    
GROWTH IN THE TRAUMA-SPINE SEGMENT TRAUMA:    
INCREASING LOCAL PRESENCE AND STRATEGIC FOCUS OF LEADING
MNCS IN INDIA    
GROWTH DRIVERS    
INCREASING INCIDENCE OF OSTEOPOROSIS, OSTEOARTHRITIS, OBESITY    
INCREASE IN AGING POPULATION    
UNTAPPED POTENTIAL AND EXPANDING HEALTHCARE ACCESS    
IMPROVEMENT IN QUALITY OF HEALTHCARE DELIVERY    
PROMOTION OF MEDICAL TOURISM    
INCREASED AVAILABILITY OF MINIMALLY INVASIVE PROCEDURES    
MARKET RESTRAINTS    
OVERALL PROCEDURE COSTS ARE OFTEN UNAFFORDABLE
LACK OF INFRASTRUCTURE CAPACITY TO PERFORM SURGERY LIMITS
ITS PENETRATION AND ADOPTION    
INTENSE COMPETITION IN THE ORTHOPEDICS MARKET    
PUBLIC HEALTHCARE SPENDING IS LOW    
MARKET SURVEY (GLOBAL)    
GLOBAL MEDICAL IMPLANTS MARKET, BY TYPE, 2016 (%)    
1) ZIMMER    
2) BIOMET    
3) DEPUY    
4) EXACTECH    
5) WALDERMAR LINK    
6) MAXX    
7) SMITH& NEPHEW    
FIGURE: DEPUY HIP    
FIGURE: STRYKER KNEE JOINT    
FIGURE: PICTURE OF X- RAY SHOWING COMPRESSED KNEE DUE
TO OSTEOARTHRITIS    
FIGURE: SCOLIOSIS: SPINE CONDITION    
FIGURE: MAJOR FACTORS AFFECTING THE INDIAN MEDICAL
DEVICES MARKET.    
GLOBAL ORTHOPEDIC PRODUCTS MARKET    
GROWTH IN ORTHOPEDIC IMPLANTS    
OUTSOURCED ORTHOPEDIC PRECISION MANUFACTURING
MARKET OVERVIEW    
INCREASED OEM OUTSOURCING    
LIST OF THE TOP 10 ORTHOPEDIC IMPLANT MANUFACTUTERS/
SUPPIERS IN THE WORLD    
DEPUY SYNTHES COMPANIES OF JOHNSON & JOHNSON    
ZIMMER BIOMET    
STRYKER    
MEDTRONIC    
ARTHREX    
SMITH & NEPHEW    
NUVASIVE    
GLOBUS MEDICAL    
WRIGHT MEDICAL GROUP    
CORIN GROUP    
PRESENT MANUFACTURES/SUPPLIERS OF ORTHOPEDIC IMPLANTS    
DETAILS OF ORTHOPAEDIC SCREW, PLATES & NAILS    
ORTHOPEDIC SCREWS:    
ORTHOPEDIC PLATES:    
INTERLOCKING NAILS (RODS):    
TECHNIQUES TO MANUFACTURE ORTHOPEDIC IMPLANT    
RAPID PROTOTYPING    
COMPUTER NUMERICAL CONTROL (CNC)    
MANUFACTURING PROCESS OF CARBON FIBER IMPLANT    
PEEK MACHINING GUIDE    
DETAILS OF ORTHOPAEDICS MACHINING    
MACHINING ISSUES    
WORK HOLDING    
TOOLING    
MATERIALS AND MACHINING    
TRACEABILITY    
FINE SELECTION    
PRODUCTS    
SPECIFICATION FOR QUALITY STANDARD    
PROCESS CAPABILITIES IN ORTHOPEDIC IMPLANTS    
7-AXIS HIGH CONTOUR MILLING:    
SWISS MICROMACHINING    
AUTOMATED DEBURRING & POLISHING    
CLEAN ROOM PACKAGING    
TESTING METHOD OF ORTHOPAEDIC    
IMPLANT & INSTRUMENTS    
METALLURGICAL ANALYSIS OF THE MATERIALS    
MICROSTRUCTURE OF THE MODIFIED SURFACE    
PHYSICAL PROPERTIES OF THE UNTREATED SUBSTRATE SURFACE    
MECHANICAL PROPERTIES - MODIFIED SURFACE    
MECHANICAL PROPERTIES - SUBSTRATE    
BIOCOMPATABILITY    
CLINICAL DATA    
MANUFACTURING    
REPORTING    
(A). MANUFACTURING PROCESS OF ORTHOPAEDIC IMPLANTS
& INSTRUMENTS    
(B). MANUFACTURING OF IMPLANT VIZ DHS/DCS PLATE    109
(C) MANUFACATURE OF IMPLANT VIZ SCREW    
MANUFACTURING PROCESS OF ORTHOPAEDIC INSTRUMENTS
(PLATING & NAILING)    
THE FOLLOWING OPERATIONS ARE CONDUCTED:-    
DETAILS OF ORTHOPAEDIC IMPLANTS MACHINING    
MACHINING ISSUES    
WORK HOLDING    
TOOLING    115
MATERIALS AND MACHINING    
TRACEABILITY    
METHOD TO ENHANCED FATIGUE PROPERTIES
OF ORTHOPAEDIC IMPLANT    
DESIGN AND PROTOTYPING    
THE DESIGN PROCESS USUALLY INVOLVES A 3D CAD MOCKUP    
MILLING    121
A QUALITY TECHNICIAN ALSO GIVES THE PARTS A LOOK OVER    
PACKING AND STERILIZATION    
LIST OF ORTHOPAEDIC IMPLANTS    
(MADE AS PER ORDER)    
(A) NAILS:-    
(B) PLATES:-    
(C) SCREWS:-    
B. ORTHOPAEDIC INSTRUMENTS    
ADVANCES IN TECHNOLOGY AND MATERIALS FOR ORTHOPAEDIC
IMPLANTS AND INSTRUMENTS    
ADVANCES IN TECHNOLOGY AND MATERIALS    
RISING PRODUCTION COSTS    
STRATEGIES FOR KEEPING COSTS DOWN    
DESIGN PROCESS FOR IMPLANTABLE    
ORTHOPAEDIC MEDICAL DEVICES    
DESIGN INPUTS    
COMMERCIAL ASPECTS    
PLANNING    
REGULATORY REQUIREMENTS    
DESIGN REQUIREMENTS    
DESIGN REVIEWS    
DESIGN    
CONCEPT DESIGN    
CONCEPT DESIGN MAY INVOLVE    
DETAIL DESIGN    
DESIGN VERIFICATION    
INTRODUCTION    
FINITE ELEMENT ANALYSIS    
RISK ANALYSIS    
RAPID PROTOTYPING    
SUPPLIERS OF RAW MATERIAL    
SUPPLIERS OF CFR PEEK    
SUPPLIERS OF PLANT AND MACHINERY    
ELECTROPLATING PLANT    
BUFFING MACHINE    

                            
APPENDIX – A:

 1.      COST OF PLANT ECONOMICS      
 2.      LAND & BUILDING                                      
 3.      PLANT AND MACHINERY                                  
 4.      FIXED CAPITAL INVESTMENT                             
 5.      RAW MATERIAL                                         
 6.      SALARY AND WAGES                                     
 7.      UTILITIES AND OVERHEADS                              
 8.      TOTAL WORKING CAPITAL                                
 9.      COST OF PRODUCTION                                   
10.      PROFITABILITY ANALYSIS                               
11.      BREAK EVEN POINT                                     
12.      RESOURCES OF FINANCE                           
13.      INTEREST CHART                                       
14.      DEPRECIATION CHART                                   
15.      CASH FLOW STATEMENT                                   
16.      PROJECTED BALANCE SHEET      
 

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