Detailed Project Report on extraction of curcumin and turmeric oil

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EXTRACTION OF CURCUMIN AND TURMERIC OIL

[CODE NO.3971]

It needs to be understood well that curcumin is an important pharmacological agent that is extracted well from turmeric rhizome. In the past, subcritical water has been used as a solvent for extraction of flavours, antioxidant components as well as fragrances from different plant materials. It needs to be noted well that subcritical water is a good solvent for curcumin as well as for other safe organic compounds. It is considered to be safer than other organic solvents. The alternative method for increasing the quality of extract refers to the subcritical water extraction of curcumin from turmeric rhizome.

The extraction and purification of natural pharmaceuticals in recent years from the medicinal plants has been noteworthy due to decreased side effects in the human body. It is well known that one of the most important medicinal plants is turmeric rhizome. This plant was used in traditional medicine, but its interest in recent years increased due to its increased use as a food colorant.

Due to presence of curcuminoids, the yellow characteristic of turmeric is quite visible. Among the curcuminoids, curcumin is the major pharmacological agent having the best of inhibitory effects for various types of cancers, which in turn arrest the activation as well as propagation of carcinogen. Research studies have indicated that curcumin produces different effects such as reduction of cholesterol, reduction of blood, myocardial infarction (MI), platelet aggregation, suppression of thrombosis and much more. Also, it suppresses symptoms associated with type-2 diabetes, Alzheimer’s disease, rheumatoid arthritis, multiple sclerosis (MS), and few more.

The extraction of curcumin and turmeric oil needs certain steps which include the following:

- Sample preparation

- Hydrodistillation

- Soxhlet Extraction

- Curcumin Quantification Analysis

- Response Surface Design

- Few more technical and scientific steps.

There is an alternative method of extraction of turmeric and turmeric oil by Continuous Water Circulation Distillation. This is one of the most important important production methods for distillation and is carried out in different ways as per the botanical material as well as the condition of the material. Three types of distillation processes are used viz. Water, Water and Steam as well as Direct Steam.

It should be understood well that water distillation is used when the plant material has been dried and will not be damaged by boiling. This material tends to come in direct contact with boiling water. Care needs to be taken that the water does not boil away and the plant material does not burn. In many research studies, much emphasis was laid on designing of continuous water circulation process which in turn increases the yield from turmeric leaves to rhizomes.

Thus, the research studies in the past have investigated upon different methods for extraction of turmeric and turmeric oil. These have been discussed in detail successfully herewith, so that it is understood well as to how the extraction process is well executed scientifically and in a technical manner, without any kind of glitches or scientific obstacle or hindrance.

COST ESTIMATION

Plant Capacity 44.5 Kg/Day

Land & Building (10,000 sq.ft.) Rs. 52 Lac

Plant & Machinery Rs. 1.26 Cr

Working Capital for 2 Months Rs. 82 Lac

Total Capital Investment Rs. 2.76 Cr

Rate of Return 33%

Break Even Point 59%

INTRODUCTION

WHAT IS TURMERIC?

WHAT IS CURCUMIN?

PRODUCT SPECIFICATION

WHAT IS THE HISTORY OF TURMERIC AND CURCUMIN?

ARE THERE ANY SIDE EFFECTS OR INTERACTIONS?

WHY HASN’T THE PHARMACEUTICAL INDUSTRY PATENTED TURMERIC

AND CURCUMIN?

DETAILS OF TURMERIC

INDIA TURMERIC GRADES AND DETAILED SPECIFICATIONS

INDIA TURMERIC GRADES

BENEFITS OF CURCUMIN AND ITS SIDE EFFECT

USES AND APPLICATION

IS MOSTLY USED IN THE FOLLOWING FIELDS:-

INDUSTRY TRENDS OF CURCUMIN

CURCUMIN MARKET, BY REGION

OPPORTUNITY AND RISE OF TURMERIC AND CURCUMIN

BIOLOGICAL SOURCE AND ACTIVITIES OF CURCUMIN

THE BIOLOGICAL SOURCE OF CURCUMIN

BIOLOGICAL ACTIVITIES OF CURCUMIN

ANTI-INFLAMMATORY PROPERTY

ANTIOXIDANT PROPERTIES

EFFECT OFCURCUMIN ON LYMPHOCYTES

EFFECT OFCURCUMIN ON PLATELET AGGREGATION

PROPERTIES OF CURCUMIN

PRODUCT DETAILS:

PRODUCT SPECIFIC LITERATURE REFERENCE:

GENERAL INFORMATION:

CHEMICAL CHARACTERIZATION OF CURCUMIN

COMPOSITION OF THE FOOD ADDITIVE

PHYSICO-CHEMICAL PROPERTIES

CURCUMIN - THE YELLOW EXTRACT FROM TURMERIC

FIGURE: CURCUMA LONGA (TURMERIC PLANT) WITH ITS RHIZOME

OR ROOT

CHEMICAL COMPOSITION OF TURMERIC

FIG: STRUCTURE OF NATURAL CURCUMINOIDS.

BIOLOGICAL ACTIVITY OF TURMERIC AND ITS COMPOUNDS

PHARMACOLOGICAL ACTION OF TURMERIC AND IT’S EXTRACT

FRAGRANCE AND FLAVOUR

RAW MATERIALS SCENARIO (INDIA AND GLOBAL)

INTERNATIONAL SCENARIO

OVERVIEW OF CURCUMIN MARKET

SCENARIO OF CURCUMIN

MARKET POSITION

CURCUMIN MARKET CAN BE SEGMENTED ON THE BASIS OF:

THERAPEUTIC APPLICATIONS

PRODUCTION OF CURCUMIN IN INDIA

GLOBAL MARKET POSITION AND DEMAND OF CURCUMIN

U.S. CURCUMIN MARKET, BY APPLICATION, 2016-2024, (TONS)

PRESENT MANUFACTURERS OF CURCUMIN

MARKET ANALYSIS OF CURCUMIN

EXTRACTION OF CURCUMIN FROM TURMERIC

SEQUENCES IN CURCUMIN EXTRACTION

PROCESS FLOW DIAGRAM

PROCESS OUTLINE FOR CURCUMIN EXTRACTION

MANUFACTURING PROCESS OF CURCUMIN

RAW MATERIAL REQUIRED:

GRADE OF CURCUMIN

BASIC PLANT AND MACHINERY REQUIRED.

SALIENT FEATURE OF THE PROCESS

MANUFACTURING PROCESS DIAGRAM

BLOCK DIAGRAM FOR CURCUMIN EXTRACTION

TECHNICAL DETAILS FOR CURCUMIN EXTRACTION

METHODS.

GRINDING OF DRIED TURMERIC AND SEPARATION

SOLVENT EXTRACTION OF TURMERIC USING ETHANOL AND WATER

SOLVENT EXTRACTION OF TURMERIC (250 Μ SIZE) USING ETHANOL

AND WATER.

MOISTURE ANALYSIS OF DRIED TURMERIC POWDER

OPTIMIZATION OF SOLVENT EXTRACTION OF TURMERIC AT DIFFERENT

TIME INTERVALS

OPTIMIZATION OF SOLVENT EXTRACTION METHOD OF TURMERIC.

SOLVENT EXTRACTION USING MIXTURE OF SOLVENT OF ETHANOL

AND WATER.

SOLVENT EXTRACTION OF TURMERIC USING PET ETHER.

QUALITATIVE ANALYSIS OF ANTIMICROBIAL ACTIVITY OF CURCUMIN

AGAINST E.COLI

RESULT AND DISCUSSION.

SOLVENT EXTRACTION OF TURMERIC (250 Μ SIZE) USING ETHANOL

AND WATER.

OPTIMIZATION OF SOLVENT EXTRACTION OF TURMERIC AT DIFFERENT

TIME INTERVALS

SOLVENT EXTRACTION USING MIXTURE OF SOLVENT OF ETHANOL

AND WATER

SOLVENT EXTRACTION OF TURMERIC USING PET ETHER

EXTRACTION AND PROCESSING OF CURCUMIN

TURMERIC HAS BEEN FOUND TO HAVE THE COMPOSITION AS SHOWN

IN TABLE BELOW

TYPICAL COMPOSITION OF TURMERIC

FIGURE: THE THREE STRUCTURES OF CURCUMIN AND OTHER CURCUMINOIDS

FIGURE TURMERIC RHIZOME AND CURCUMIN THAT WAS EXTRACTED

REFINEMENT OF CURCUMIN:

FILTRATION:

OLEORESIN TO CURCUMIN:

FIGURE – OLEORESIN TO CURCUMIN REFINEMENT PROCESS SET-UP

PURITY TESTING TECHNIQUES:

METHOD OF SUBCRITICAL CURCUMIN EXTRACTION

ANALYSIS OF TURMERIC OIL

MATERIALS AND METHODS

PLANT RAW MATERIAL

FIGURE: FRESH TURMERIC RHIZOMES

DESCRIPTION OF EXPERIMENTAL SETUP AND METHOD

FIGURE: PROCESS FLOW DIAGRAM FOR PRODUCTION OF TURMERIC OIL

CALCULATION OF OIL YIELD AND MOISTURE CONTENT

MOISTURE CONTENT

TURMERIC OIL YIELD

SWOT ANALYSIS OF CURCUMIN

STRENGTH

OPPORTUNITIES

WEAKNESSES

THREAT

LICENSES, CERTIFICATE AND QUALITY CONTROL FOR CURCUMIN

EXTRACTION

FSSAI

AYUSH LICENSE (FOR MULTI PURPOSE EXTRACTION)

NOC

BUYERS LIST OF CURCUMIN AND TURMERIC OIL

SUPPLIERS OF RAW MATERIAL (INDIAN)

SUPPLIERS OF N-HAXANE

SUPPLIERS OF LABORATORY CHEMICALS

SUPPLIERS OF RAW MATERIAL (GLOBAL)

SUPPLIERS OF PLANT AND MACHINRY (IMPORTED)

TURNKEY SUPPLIERS OF CURCUMIN EXTRACTION

SUPPLIERS OF PLANT AND MACHINRY

SUPPLIERS OF CRUSHER

SUPPLIERS OF EVAPORATORS

SUPPLIERS OF FILTER PRESS

SUPPLIERS OF BOILERS

SUPPLIERS OF LAB TESTING EQUIPMENT

SUPPLIERS OF STORAGE TANK

SUPPLIERS OF MATERIAL HANDLING EQUIPMENTS

SUPPLIERS OF EXTRACTOR

SUPPLIERS OF STEAM DISTILATION PLANT

SUPPLIERS OF PUMPS

SUPPLIERS OF DIGITAL WEIGHING SCALE

SUPPLIERS OF OTHER MACHINERY

APPENDIX – A:

01. PLANT ECONOMICS

02. LAND & BUILDING

03. PLANT AND MACHINERY

04. OTHER FIXED ASSESTS

05. FIXED CAPITAL

06. RAW MATERIAL

07. SALARY AND WAGES

08. UTILITIES AND OVERHEADS

09. TOTAL WORKING CAPITAL

10. TOTAL CAPITAL INVESTMENT

11. COST OF PRODUCTION

12. TURN OVER/ANNUM

13. BREAK EVEN POINT

14. RESOURCES FOR FINANCE

15. INSTALMENT PAYABLE IN 5 YEARS

16. DEPRECIATION CHART FOR 5 YEARS

17. PROFIT ANALYSIS FOR 5 YEARS

18. PROJECTED BALANCE SHEET FOR (5 YEARS)

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